Vine Leaf
Vitis vinifera
A Strong clinical evidenceVine leaf extract may help chronic venous insufficiency with swollen, heavy legs; vine leaf tea is used traditionally for heavy legs.
Image: Herbadex Botanik Stüdyosu · Özel Üretim
On this page
At a glance
The EMA classes standardised aqueous dry extract of vine leaf as "well-established use" for chronic venous insufficiency with swollen legs, varicose veins, heaviness and cramps. Vine leaf tea is traditionally used for heavy, uncomfortable legs due to minor venous circulation problems.
Updated: October 15, 2026
✓ This herb record is backed by official European Medicines Agency (EMA HMPC) herbal monographs.
What is it used for?
A Strong clinical evidence
Strong clinical evidence: Supported by strong human clinical trials and well-established medicinal use monographs.
How do we rate evidence levels? →Standardised extract may help with chronic venous insufficiency marked by swollen legs, varicose veins, heaviness and cramps. [1]
T Traditional use
Traditional use: Based on at least 30 years of documented traditional use rather than clinical trials.
How do we rate evidence levels? →Leaf tea is traditionally used for heavy, uncomfortable legs due to minor venous circulation problems. [1]
How is it used?
Safety & interactions
Minimum age: 18 years
- See a doctor for sudden leg swelling, skin inflammation, hardening, ulcers, severe pain, or heart or kidney failure.
- See a doctor if there is not enough improvement within 2 weeks; swelling may have other causes.
- Not recommended under 18. Not recommended in pregnancy or breastfeeding because safety has not been shown.
Drug interactions
No recorded interactions
Side effects
- Itching, redness, hives
- Nausea, stomach complaints, headache
⚕ When to see a doctor
- If high fever, shortness of breath or purulent/bloody phlegm develops
- If symptoms do not improve within 1–2 weeks or worsen
- If severe abdominal pain, jaundice, rash or allergic reaction occurs
Did you know?
The effect of red vine leaf on leg vein complaints falls under the EMA's clinically supported "well-established use". [1]
Frequently asked questions
Does vine leaf help varicose veins?
Based on clinical data, the EMA accepts that standardised vine leaf extract may help swelling and heaviness in chronic venous insufficiency.
How do I make vine leaf tea?
Pour 250 ml of boiling water over 5–10 g of dried leaf; drink twice a day.
Is it the same as culinary vine leaves?
It is the same plant, but the assessment covers medicinal extract and tea.
How long is it used?
The recommended course for the extract is 12 weeks; effects begin within 2–3 weeks.
Sources
Cite This Page
Vine Leaf (Vitis vinifera). Herbadex — Doğal Şifa Rehberi (2026). https://herbadex.com/en/herb/vine-leaf/
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