Buckthorn Seed
Rhamnus cathartica
T Traditional useAnthraquinone-containing fruits with a very strong laxative effect. Used only short term and at low doses for occasional constipation.

Image: Herbadex Botanik Stüdyosu · Özel Üretim
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At a glance
Buckthorn "seeds" are the ripe fruits of Rhamnus, containing the same anthraquinone stimulant laxatives as senna and frangula bark. They are traditionally used for constipation and can act harshly. There are no clinical studies, and long-term use of this laxative group causes loss of water and potassium.
Updated: October 15, 2026
ℹ Compiled from standard pharmacognosy references and clinical literature summaries where no formal EMA monograph exists.
What is it used for?
T Traditional use
Traditional use: Based on at least 30 years of documented traditional use rather than clinical trials.
How do we rate evidence levels? →Traditionally used as a stimulant laxative for occasional constipation. [1]
How is it used?
Food
Adults: swallow 2–3 fruits with plenty of water at bedtime; use the lowest effective amount.
Amount: At most once daily
Duration limit: 1 week
[1]Safety & interactions
Minimum age: 12 years
Duration limit: 7 days
- Do not use for more than 1 week; long-term use can cause a sluggish bowel, laxative dependence and potassium loss.
- Do not use with bowel obstruction, appendicitis, Crohn's disease, ulcerative colitis, unexplained abdominal pain or dehydration.
- Do not use in children under 12, in pregnancy or while breastfeeding.
- Fresh fruits can cause vomiting and severe diarrhoea; use dried fruits only.
Drug interactions
| Medicine / substance | Effect | Severity |
|---|---|---|
| Cardiac glycosides (e.g. digoxin), antiarrhythmics | Low potassium can increase their effects and side effects. [2] | Major |
| Diuretics, corticosteroids, liquorice root | May increase potassium loss. [2] | Moderate |
Side effects
- Abdominal cramps and watery stools
- Loss of water and electrolytes with long-term use
- Reddish urine
⚕ When to see a doctor
- If high fever, shortness of breath or purulent/bloody phlegm develops
- If symptoms do not improve within 1–2 weeks or worsen
- If severe abdominal pain, jaundice, rash or allergic reaction occurs
Did you know?
Buckthorn berries were once also used to make yellow and green dyes. [1]
Frequently asked questions
Does buckthorn help weight loss?
No. Using laxatives to lose weight is dangerous; the weight lost is water, and potassium loss can upset heart rhythm.
How long can buckthorn be used?
At most 1 week and only when needed. If you need a laxative daily, the cause should be investigated.
Is buckthorn the same as senna?
They are different plants but contain similar anthraquinones, so their effects and risks are similar.
Sources
- ESCOP Monographs: The Scientific Foundation for Herbal Medicinal ProductsESCOP · 2019
- EFSA Compendium of Botanicals Reported to Contain Naturally Occurring Substances of Possible ConcernEFSA · 2022
Cite This Page
Buckthorn Seed (Rhamnus cathartica). Herbadex — Doğal Şifa Rehberi (2026). https://herbadex.com/en/herb/buckthorn-seed/
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